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صفحه اصلی
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بیست و نهمین کنفرانس شیمی آلی ایران
A3 coupling reaction in the presence of Fumed-Pr-Pi@Ag
نویسندگان :
Masoome Atef ( دانشگاه الزهرا(س) ) , Ghodsi Mohammadi ziarani ( دانشگاه الزهرا(س) )
کلید واژه ها :
Nano catalyst،Fumed silica،A3 coupling reactions،Propargyl amines
چکیده مقاله :
According to the economical aspect of the chemical reaction, the heterogeneous catalytic system was attracted the researcher’s attentions due to their simple separation process and also their recoverability [1]. Among the various solid supports, the Fumed silica is one of the most applicable candidate due to its amorphous structure, low density, high specific surface area, and also the nano size of the particles (5-50 nm) [2]. So, in this research, the Fumed silica was functionalized by (3-chloropropyl)-triethoxysilane, piperazine [3]. Subsequently, the silver was immobilized on the surface of Fumed silica to obtain Fumed-Pr-Pi@Ag as the efficient heterogeneous catalyst, which was used in the A3 coupling reaction to produce propargyl amines which are active in biological compounds (e.g., antitumor and antioxidant)[4]
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