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صفحه اصلی
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بیست و نهمین کنفرانس شیمی آلی ایران
Green and efficient synthesis of pyranopyrazole derivatives using SBA-15 supported ionic liquid (SBA-IL)
نویسندگان :
Sara Mohseni Tavana ( دانشگاه الزهرا(س) ) , Ghodsi Mohammadi Ziarani ( دانشگاه الزهرا(س) )
کلید واژه ها :
Pyranopyrazole،Multicomponent reaction،SBA-IL،Heterogeneous catalyst
چکیده مقاله :
Dihydropyrano[2,3-c]pyrazole derivatives are a significant class of heterocyclic compounds known for their pharmaceutical activities [1]. The synthesis of these compounds involves a multicomponent reaction of ethyl acetoacetate, hydrazine hydrate, malononitrile, and aldehyde/ketone [2]. Ionic liquids are considered environmentally friendly alternatives because they can exhibit low environmental toxicities. As a result, researchers have been attracted to using ILs in various applications, including catalysis [3]. In This research, The reaction is conducted using SBA-IL as an efficient and heterogeneous catalyst in short reaction time with acceptable yield, which offers advantages such as easy separation and reusability (Scheme 1). The use of ionic liquids (ILs) in this research is particularly interesting due to their "green" nature.
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