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صفحه اصلی
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بیست و نهمین کنفرانس شیمی آلی ایران
The Biginelli reaction promoted by choline chloride based deep eutectic solvents for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones
نویسندگان :
فاطمه جنتی ( پیام نور )
کلید واژه ها :
Biginelli reaction،Deep eutectic solvent،L-Prplin
چکیده مقاله :
Biginelli condensation of β-keto ester, benzaldehyde and urea catalyzed by L-proline in the choline chloride -based deep eutectic solvents was achieved. High yields are up to 93.6%. Mild reaction conditions, enhanced rates, improved yields, recyclability of deep eutectic solvents containing L-proline, and reagents’ reactivity which is different from that in standard organic solvents are the remarkable features observed in deep eutectic solvents. The deep eutectic solvents containing catalyst was recycled in three subsequent runs with no decrease in activity.
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