0% Complete
صفحه اصلی
/
بیست و نهمین کنفرانس شیمی آلی ایران
Synthesis of 1,2,3-triazolyl-pyridine derivatives through a multicomponent reactions and using a new nano-magnetic catalyst based on urea
نویسندگان :
Monireh Navazeni ( دانشگاه بو علی سینا همدان ) , Morteza Torabi ( دانشگاه بو علی سینا همدان ) , Mohammad Ali Zolfigol ( دانشگاه بو علی سینا همدان ) , Ardeshir Khazaei ( دانشگاه بو علی سینا همدان ) , Kaveh Khosravi ( دانشگاه اراک )
کلید واژه ها :
Urea،1,2,3-triazole pyridine،Nano-magnetic catalyst
چکیده مقاله :
Herein, we have designed a recyclable, reusable and environmentally friendly urea-containing catalyst which is modified on magnetic nanoparticles surface and can use in the manufacture of valuable chemical compounds. Then, by using this catalyst, a new class of derivatives 1,2,3-triazolyl-pyridine was synthesized in solvent-free conditions. The results showed that this catalyst has a good efficiency in the synthesis of the mentioned compounds due to the dispersion of nanoparticles, and the strong interactions of linker on the nanoparticle surface, as well as the interaction of hydrogen donor species with the compounds present in reactions. Because of having pyridine ring, substitution containing 1,2,3-triazole and as well as -NH2 and -CN functional groups in position 2 and 3 [1], the synthesized compounds have properties such as antimicrobial, antitumor, anticancer, antifungal, antibacterial, antiinflammatory, alpha reductase inhibitors, LSD1 inhibitors and alpha glycosidase inhibitors. Therefore, they are widely used as a precursor for the preparation of molecules that have various medicinal and biological applications [2].
لیست مقالات این رویداد
ثمین همایش، سامانه مدیریت کنفرانس ها و جشنواره ها
