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صفحه اصلی
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بیست و نهمین کنفرانس شیمی آلی ایران
Effect of temperature on solubility and thermal stability of Triamterene drug in subcritical water
نویسندگان :
Maryam Khajenoori ( دانشگاه سمنان ) , Mina Delkhani ( دانشگاه سمنان ) , Ali Haghighi Asl ( دانشگاه سمنان )
کلید واژه ها :
Solubility،Triamterene،Subcritical water
چکیده مقاله :
Subcritical water at temperatures less than 374°C has the property of constant dielectric adjustment, which turns water into a green and safe solvent for poorly soluble drugs. In this research, the effect of temperature on the solubility of Triamterene (a diuretic drug) in subcritical water was investigated by a static method. The experiments were performed under a constant pressure of 30 bar and at temperatures between 383.15-443.15 K. With increasing temperature, the mole fraction solubility of the drug increased .from 0.782×10-4 to 1.399×10-4
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