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بیست و نهمین کنفرانس شیمی آلی ایران
Synthesis of 1,4-dihydropyridine by magnetic nanoparticles (NiFe2o4) as a catalyst
نویسندگان :
Tannaz Mahmoudi ( دانشگاه علم و صنعت ایران ) , Seyyed Hojjat Sadeghi ( دانشگاه علم و صنعت ایران ) , Zahra Karbalaie ( دانشگاه علم و صنعت ایران ) , Sadegh Rostamnia ( دانشگاه علم و صنعت ایران )
کلید واژه ها :
magnetic nanoparticles،1،4-dihydropyridine،nickel ferrite
چکیده مقاله :
One of the key components of chemical reactions is catalysis, which provides selectivity, a high yield of the products, and faster reaction rates.The use of magnetic nanoparticles (MNPs) of transition metal oxides as solid supports has recently received a lot of research attention. They are simple to make and good candidates to immobilize a variety of homogeneous catalysts due to the extreme surface area of nanoparticles, stability, magnetic characteristics, and inherent electronic impact of transition metal elements. The use of cubic spinel nickel ferrite (NiFe2O4) has been researched in this area. For simple separation from the reaction mixture, this magnetic material's excellent heat stability (up to 900 ˚C) and superparamagnetic properties are advantageous. 1 DHPs, or 1,4-dihydropyridine derivatives, are present in a wide variety of pharmacological substances. Due to their many therapeutic and medical properties, these chemicals have attracted a lot of interest. These are medicines that can be used to protect the liver and dilate blood vessels. The DHPs also function as anti-aging, anti-tumor, anti-asthma, and anti-diabetic medications. As a result, many different techniques have been described for the synthesis of 1,4-dihydropyridine derivatives up to this point. 2
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