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صفحه اصلی
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بیست و نهمین کنفرانس شیمی آلی ایران
Choline chloride-urea as a solvent/catalyst for the synthesis of 2-aminoimidazopyridines
نویسندگان :
Amin Parvizi moghadam ( دانشگاه صنعتی نوشیروانی بابل ) , Afshin Sarvary ( دانشگاه صنعتی نوشیروانی بابل ) , Negin Dehghan ( دانشگاه صنعتی نوشیروانی بابل )
کلید واژه ها :
Deep eutectic solvent،imidazopyridine،Choline chloride-urea،green chemistry
چکیده مقاله :
Imidazo[2,1-α] pyridine heterocycle is important in the base of drugs such as Alpidem, Zolpidem and Olprinone. in the present study, the three-component reaction between aldehyde, 2-aminopyridine, and KCN in choline chloride-urea deep eutectic solvent (DES) was used for the synthesis of imidazopyridine. this reaction is completely carried out in a single container in a test tube, and the reaction efficiency is very favourable. choline chloride-urea is an environmentally friendly solvent/catalyst, which has importance and value in green chemistry.
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