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صفحه اصلی
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بیست و نهمین کنفرانس شیمی آلی ایران
Synthesis new derivatives of 1-methyl-3-phenylpyrazolo[4',3':5,6]pyrano[3,4-c]quinolin-5(3H)-one and 1H-pyrimido[5',4':5,6]pyrano[3,4-c]quinoline-1,3,6(2H,4H)-trione compounds
نویسندگان :
Sobhan Ghazimoradi ( دانشگاه صنعتی خواجه نصیرالدین طوسی ) , Sorour Ramezanpour ( دانشگاه صنعتی خواجه نصیرالدین طوسی )
کلید واژه ها :
Quinolines،Multicomponent،activity
چکیده مقاله :
In this research, we have been able to synthesize different derivatives of two groups of 1-methyl-3-phenylpyrazolo [4',3':5,6] pyrano[3,4-c] quinolin-5(3H)-one(a) and 1H-pyrimido [5',4':5,6] pyrano [3,4-c] quinoline-1,3,6(2H,4H)-trione(b) compounds using multicomponent reactions with a similar method. 1-Methyl-3-phenylpyrazolo[4',3':5,6]pyrano[3,4-c]quinolin-5(3H)-one(a) compounds based on their structural skeleton can show properties such as: antibacterial, antioxidant1, anti-cancer activity2, Also, and 1H-pyrimido[5',4':5,6]pyrano[3,4-c]quinoline-1,3,6(2H,4H)-trione(b) Important scaffolding in organic and medicinal chemistry, with activities such as 5-HT3 receptor antagonist, topoisomerase II inhibitors, etc3. In this research, for the first time, we were able to synthesize a new class of them.. You can see the overall reactions of those two families of compounds in the Scheme1.
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